Trypanothione synthetase-IN-3

• UNSPSC Description:

  Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum[1].

• Target Antigen:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/trypanothione-synthetase-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2[C@H]([C@H](O[C@@H]([C@H]2OC(C3=CC(O)=C(C(O)=C3)O)=O)COC(C4=CC(O)=C(C(O)=C4)O)=O)O[C@@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COC(C6=CC(O)=C(C(O)=C6)O)=O)OC(C7=CC(O)=C(C(O)=C7)O)=O)OC(C8=CC(O)=C(C(O)=C8)O)=O)OC(C9=CC(O)=C(C(O)=C9)O)=O)OC(C%10=CC(O)=C(C(O)=C%10)O)=O

• Molecular Weight:

  1559.13

• References & Citations:

  [1]Mercedes Alcón-Calderón, et al. Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library. European Journal of Medicinal Chemistry, 2022, 114675.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1314875-96-1