Trypanothione synthetase-IN-3

Trypanothione synthetase-IN-3

• CAS Number: 1314875-96-1
• UNSPSC Description: Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum[1].
• Target Antigen: Parasite
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/trypanothione-synthetase-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2[C@H]([C@H](O[C@@H]([C@H]2OC(C3=CC(O)=C(C(O)=C3)O)=O)COC(C4=CC(O)=C(C(O)=C4)O)=O)O[C@@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COC(C6=CC(O)=C(C(O)=C6)O)=O)OC(C7=CC(O)=C(C(O)=C7)O)=O)OC(C8=CC(O)=C(C(O)=C8)O)=O)OC(C9=CC(O)=C(C(O)=C9)O)=O)OC(C%10=CC(O)=C(C(O)=C%10)O)=O
• Molecular Weight: 1559.13
• References & Citations: [1]Mercedes Alcón-Calderón, et al. Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical library. European Journal of Medicinal Chemistry, 2022, 114675.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported