Trypanothione

• UNSPSC Description:

  Trypanothione is a bis-glutathionyl derivative, found in trypanosomatids. Trypanothione shows the protection against oxidative stress[1][2][3].

• Target Antigen:

  Drug Derivative

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/trypanothione.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC([C@@H](N)CCC(N[C@@H]1C(NCC(NCCCCNCCCNC(CNC([C@H](CSSC1)NC(CC[C@H](N)C(O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  721.85

• References & Citations:

  [1]Manta B, et al. Trypanothione: a unique bis-glutathionyl derivative in trypanosomatids. Biochim Biophys Acta. 2013 May;1830(5):3199-216.|[2]Fairlamb AH, et al. Metabolism and functions of trypanothione in the Kinetoplastida. Annu Rev Microbiol. 1992;46:695-729.|[3]Krauth-Siegel RL, et al. The parasite-specific trypanothione metabolism of trypanosoma and leishmania. Biol Chem. 2003 Apr;384(4):539-49.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  96304-42-6