Trypanothione

• Description :

  Trypanothione is a bis-glutathionyl derivative, found in trypanosomatids. Trypanothione shows the protection against oxidative stress[1][2][3].

• UNSPSC :

  12352005

• Target :

  Drug Derivative

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/trypanothione.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC([C@@H](N)CCC(N[C@@H]1C(NCC(NCCCCNCCCNC(CNC([C@H](CSSC1)NC(CC[C@H](N)C(O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C27H47N9O10S2

• Molecular Weight :

  721.85

• References & Citations :

  [1]Manta B, et al. Trypanothione: a unique bis-glutathionyl derivative in trypanosomatids. Biochim Biophys Acta. 2013 May;1830 (5) :3199-216.|[2]Fairlamb AH, et al. Metabolism and functions of trypanothione in the Kinetoplastida. Annu Rev Microbiol. 1992;46:695-729.|[3]Krauth-Siegel RL, et al. The parasite-specific trypanothione metabolism of trypanosoma and leishmania. Biol Chem. 2003 Apr;384 (4) :539-49.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [96304-42-6]