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NAD Synthetase

CAT: 0804-HY-E70410-01Size: 5 KUDry Ice: NoHazardous: No
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CAT#:0804-HY-E70410-01Size:5 KU
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NAD synthetase is responsible for the final step in the synthesis of nicotinamide adenine dinucleotide (NAD) . The Km values for NAD, ATP, and ammonia of NAD synthetase from Escherichia coli are 200 μM, 11 μM, and 0.65 μM, respectively, while the Km values for NAD, ATP, and ammonia of NAD synthetase from yeast are 170 μM, 190 μM, and 64 μM, respectively. NAD synthetase can be used for enzymatic assays to determine ATP, ammonia, urea, or creatinine, and is also suitable for enzymatic cycling methods. Additionally, NAD synthetase holds potential for research into metabolic diseases, cancer, aging, and neurodegenerative diseases[1][2].
CAS Number
9032-69-3
Product Name Alternative
NAD+ Synthetase; Nicotinamide adenine dinucleotide synthetase
UNSPSC
12352204
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nad-synthetase.html
Smiles
[NADSynthetase]
References & Citations
[1]Zalkin H. NAD synthetase. Methods Enzymol. 1985;113:297-302.|[2]Xie N, et al. NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential. Signal Transduct Target Ther. 2020 Oct 7;5 (1) :227.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported

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