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S07-2001

CAT: 0804-HY-150650Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-150650Size:1 Each
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Description
S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer agent resistance[1].
CAS Number
1197904-57-6
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s07-2001.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C(C)=O)=CN1)NCC2=CC=C(CS(=O)(N)=O)C=C2
Molecular Formula
C15H17N3O4S
Molecular Weight
335.38
References & Citations
[1]Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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