S07-2001

• Description :

  S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer agent resistance[1].

• UNSPSC :

  12352005

• Target :

  Aldose Reductase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/s07-2001.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC(C(C)=O)=CN1)NCC2=CC=C(CS(=O)(N)=O)C=C2

• Molecular Formula :

  C15H17N3O4S

• Molecular Weight :

  335.38

• References & Citations :

  [1]Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1197904-57-6]