ODN 2007

• Description :

  ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3'[1][2][3].

• CAS Number :

  [455348-63-7]

• UNSPSC :

  12352208

• Hazard Statement :

  H315, H319, H335

• Target :

  Toll-like Receptor (TLR)

• Type :

  Oligonucleotides

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/odn-2007.html

• Purity :

  93.51

• Solubility :

  H2O : 20 mg/mL (ultrasonic)

• Smiles :

  [DNA,d(P-thio)(T-C-G-T-C-G-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T)]

• Molecular Weight :

  6852.50

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Tamiru N Alkie, et al. Characterization of Innate Responses Induced by PLGA Encapsulated- and Soluble TLR Ligands In Vitro and In Vivo in Chickens. PLoS One. 2017 Jan 3;12 (1) :e0169154. |[2]Hua Chen, et al. CpG-ODN 2007 protects zebrafish (Danio rerio) against Vibrio vulnificus infection. Aquac Res. 2021; 52: 897-905.|[3]Audesh Bhat, et al. Role of Hsp90 in CpG ODN mediated immunostimulation in avian macrophages. Mol Immunol. 2010 Mar;47 (6) :1337-46.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Oligonucleotides

• Clinical Information :

  No Development Reported