SC-2001

• Description:

  SC-2001 is a compound structurally related to obatoclax that has better antitumor effects than obatoclax in liver cancer cell lines, downregulating Mcl-1 protein levels, inhibiting STAT3 phosphorylation, inducing apoptosis, and enhancing SHP1 expression and activity.

• UNSPSC:

  12352005

• Target:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/sc-2001.html

• Concentration:

  10mM

• Purity:

  99.37

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  COC1=C(/C=C2N=CC=C/2)NC(C(N3)=CC4=C3C=CC(Br)=C4)=C1

• Molecular Formula:

  C18H14BrN3O

• Molecular Weight:

  368.23

• References & Citations:

  [1]A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1383727-17-0]