SC-2001

• Description :

  SC-2001 is a compound structurally related to obatoclax that has better antitumor effects than obatoclax in liver cancer cell lines, downregulating Mcl-1 protein levels, inhibiting STAT3 phosphorylation, inducing apoptosis, and enhancing SHP1 expression and activity.

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/sc-2001.html

• Concentration :

  10mM

• Purity :

  99.37

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  COC1=C(/C=C2N=CC=C/2)NC(C(N3)=CC4=C3C=CC(Br)=C4)=C1

• Molecular Formula :

  C18H14BrN3O

• Molecular Weight :

  368.23

• References & Citations :

  [1]A novel obatoclax derivative, SC-2001, induces apoptosis in hepatocellular carcinoma cells through SHP-1-dependent STAT3 inactivation

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1383727-17-0]