Products for Research Use Only
RegisterLogin

S07-1066

CAT: 0804-HY-155035-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-155035-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
S07-1066 is an aldo-keto reductase 1C3 (AKR1C3) inhibitor, synergizing doxorubicin (DOX) cytotoxicity. S07-1066 selectively blocks AKR1C3-mediated reduction of DOX, and reverses the DOX resistance in overexpressing AKR1C3 cells[1].
CAS Number
876625-29-5
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s07-1066.html
Concentration
10mM
Purity
99.48
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC(Cl)=CC(C2=CC=C(C3(C(O)=O)CC3)C=C2F)=C1
Molecular Formula
C16H11Cl2FO2
Molecular Weight
325.16
References & Citations
[1]He S, et al. Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment. J Med Chem. 2023 Jul 6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-129318MBX-1066
HY-150648S07-2008
HY-150644-01S07-2010
HY-150646S07-2009
HY-150650S07-2001
HY-150649S07-2005 (racemic)
HY-19914-01MK-1064
HY-125858-01MI-1061
HY-105466P-1060
HY-D1449-01IR-1061

Alternative Products

CatalogName
GTR19219902S07-1066
ARC0854SNU-1066
MBS132358-01WP 1066
T88733-01MBX-1066
PG017CMRL-1066
99-603-CVCMRL 1066 SUPPLEMENTED
T62373-01S07-2008
T61033-01S07-2001
MBS5804189S07-2010
T61003-01S07-2009

Popular Products