S07-2008

• Description :

  S07-2008 is a selective aldo-keto reductase family 1 member C3 (AKR1C3) inhibitor with an IC50 of 0.16 μM. S07-2008 shows anticancer activities[1].

• UNSPSC :

  12352005

• Target :

  Aldose Reductase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/s07-2008.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NCCC1=CC=C(S(=O)(N)=O)C=C1)C2=CC=CC=C2OCC3=C(C)ON=C3C

• Molecular Formula :

  C21H23N3O5S

• Molecular Weight :

  429.49

• References & Citations :

  [1]Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Medicinal Chemistry Letters, 2022.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1090816-80-0]