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S07-2008

CAT: 0804-HY-150648Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-150648Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S07-2008 is a selective aldo-keto reductase family 1 member C3 (AKR1C3) inhibitor with an IC50 of 0.16 μM. S07-2008 shows anticancer activities[1].
CAS Number
1090816-80-0
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s07-2008.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCC1=CC=C(S(=O)(N)=O)C=C1)C2=CC=CC=C2OCC3=C(C)ON=C3C
Molecular Formula
C21H23N3O5S
Molecular Weight
429.49
References & Citations
[1]Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Medicinal Chemistry Letters, 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported