Antitumor agent-112

• Description:

  Antitumor agent-112 (compound 3a) is a potent antitumor agent. Antitumor agent-112 induces apoptosis. Antitumor agent-112 has cytotoxic activity on A549 cells with an IC50 value of 91.35 μM[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/antitumor-agent-112.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N/N=C/C1=CC=C(N(C)C)C=C1)CSC2=NC3=CC(Cl)=CC=C3O2

• Molecular Formula:

  C18H17ClN4O2S

• Molecular Weight:

  388.87

• References & Citations:

  [1]Erdönmez B, et, al. Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy. ACS Omega. 2023 May 24;8 (22) :20056-20065.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4