CP-07

CAT: 0804-HY-149495Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149495Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CP-07 is a potent and selective PROTACCDK9 degrader (DC50: 43 nM) . CP-07 inhibits 22RV1 cell proliferation (IC50: 62 nM) and colony formation by down-regulating Mcl-1 and c-Myc. CP-07 inhibits 22RV1 xenograft tumor growth. CP-07 can be used for research of prostate cancer[1].
UNSPSC
12352005
Target
CDK; PROTACs
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cp-07.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(O)=C(C(C=C(C2=CC=C(N3CCN(CC4CCN(C5=CC=C(C(N(C6CCC(NC6=O)=O)C7=O)=O)C7=C5)CC4)CC3)C=C2)O8)=O)C8=C1C9=CCN(C)CC9
Molecular Formula
C45H48N6O8
Molecular Weight
800.90
References & Citations
[1]Wu T, et al. Discovery of novel flavonoid-based CDK9 degraders for prostate cancer treatment via a PROTAC strategy. Eur J Med Chem. 2023 Nov 15;260:115774.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK9

Related Products

CatalogName
HY-162886BSO-07
HY-106156Allotrap 07
HY-108003-01MM 07
HY-144308RMS-07
HY-125158HOI-07
HY-172590LZ-07
HY-163912JZD-07
HY-131031-01KCC-07
HY-100494-01SH5-07
HY-105315AFP-07

Alternative Products

CatalogName
MBS5820498CP-07
sc-81889L-type Ca++ CP γ3 (A-07)
STJ501223Anti-07/02/07
C18069SH5-07 (SH-5-07)
MBS5812272ADA-07
BA6425-1SH5-07
MBS5759340KCC-07
MBS5773424AFP-07
MBS5774600TBZ-07
M30642-01MM 07

Popular Products