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AFP-07

CAT: 0804-HY-105315Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105315Size:1 Each
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Description
AFP-07 is a derivative of 7, 7-difluoroprostacyclic and is a highly potent and selective prostacyclin receptor IP receptor agonist with a Ki value of 0.561 nM[1].
CAS Number
171232-82-9
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/afp-07.html
Smiles
CCC#CC[C@H](C)[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@@](C[C@H]1O)([H])O/C(C2(F)F)=C\CCCC(O[Na])=O
Molecular Formula
C22H29F2NaO5
Molecular Weight
434.45
References & Citations
[1]Chang CS, et al. 7,7-Difluoroprostacyclin derivative, AFP-07, a highly selective and potent agonist for the prostacyclin receptor. Prostaglandins. 1997 Feb;53 (2) :83-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported