Allotrap 07

• Description :

  Allotrap 07 is a synthetic peptide composed of residues 75-84 of HLA-B7, a class I MHC molecule. Allotrap 07 combined with Cyclosporin A (HY-B0579) induces donor-specific tolerance in rat cardiac allografts, significantly prolonging graft survival[1].

• UNSPSC :

  12352005

• Target :

  MHC

• Related Pathways :

  Immunology/Inflammation

• Field of Research :

  Inflammation/Immunology; Cardiovascular Disease

• Smiles :

  OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C53H90N20O16

• Molecular Weight :

  1263.41

• References & Citations :

  [1]Masroor S, et al. Induction of tolerance in rodent cardiac allotransplantation using an MHC class I-derived peptide and cyclosporin A. Ann Thorac Surg. 1998 Jan;65 (1) :144-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [151232-75-6]