MM 07

• Description:

  MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart.

• UNSPSC:

  12352209

• Target:

  Apelin Receptor (APJ)

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/MM_07.html

• Purity:

  99.95

• Solubility:

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles:

  O=C([C@H]1N(CCC1)C(CNC([C@H](CCCCN)NC([C@@H](NC([C@H]2NC([C@](NC([C@@H](NC([C@@]3([H])N(CCC3)C([C@@](CCCNC(N)=N)([H])NC([C@@H](N)CSSC2)=O)=O)=O)CCCNC(N)=N)=O)([H])CC(C)C)=O)=O)CC4=CN=CN4)=O)=O)=O)N[C@@H](CCSC)C(N5[C@@H](CCC5)C(N[C@H](C(O)=O)CC6=CC=CC=C6)=O)=O

• Molecular Formula:

  C67H106N22O14S3

• Molecular Weight:

  1539.89

• References & Citations:

  [1]Brame AL, et al. Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonist. Hypertension. 2015 Apr;65 (4) :834-40.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1876450-21-3]