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MM 07

CAT: 0804-HY-108003-01Size: 1 mgDry Ice: NoHazardous: No
CAT#: HY-108003-01Size: 1 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart.
CAS Number
[1876450-21-3]
UNSPSC
12352209
Target
Apelin Receptor (APJ)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/MM_07.html
Purity
99.95
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(CCC1)C(CNC([C@H](CCCCN)NC([C@@H](NC([C@H]2NC([C@](NC([C@@H](NC([C@@]3([H])N(CCC3)C([C@@](CCCNC(N)=N)([H])NC([C@@H](N)CSSC2)=O)=O)=O)CCCNC(N)=N)=O)([H])CC(C)C)=O)=O)CC4=CN=CN4)=O)=O)=O)N[C@@H](CCSC)C(N5[C@@H](CCC5)C(N[C@H](C(O)=O)CC6=CC=CC=C6)=O)=O
Molecular Formula
C67H106N22O14S3
Molecular Weight
1539.89
References & Citations
[1]Brame AL, et al. Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonist. Hypertension. 2015 Apr;65 (4) :834-40.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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