Apoptosis inducer 7

• Description:

  Apoptosis inducer 7 (Compound 5I) induces apoptosis in cancer cells. Apoptosis inducer 7 inducrs cleavage of PARP, caspases, down-regulation of anti-apoptotic protein c-Flip and up regulation of pro-apoptotic protein Noxa. Apoptosis inducer 7 exhibits antitumor activity[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/apoptosis-inducer-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@]12[C@@](C(C=C3[C@]2(CC[C@@]4([C@@]3([H])C[C@](C)(CC4)C(OCC5=CC=CC=C5)=O)C)C)=O)([H])[C@@]6([C@@](C(C)(C(/C(C6)=C/C(NC7CCN(CC7)C(OC(C)(C)C)=O)=O)=O)C)([H])CC1)C

• Molecular Formula:

  C49H68N2O7

• Molecular Weight:

  797.07

• References & Citations:

  [1]Huang M, et al. Synthesis and antitumor effects of novel 18β-glycyrrhetinic acid derivatives featuring an exocyclic α, β-unsaturated carbonyl moiety in ring A. Bioorg Chem. 2020 Oct;103:104187.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2252278-57-0