STING modulator-4

• Description :

  STING modulator-4 (compound AIH05) is a competitive STING modulator with a Ki of 0.0933 μM for R232H STING. STING modulator-4 has an EC50 of >10 μM for p-IRF3 in THP-1 cell[1].

• UNSPSC :

  12352005

• Target :

  STING

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/sting-modulator-4.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC2=C(C=NN2C)C(C3=NC(C4=CC=NN4CC)=CN3C)=N1)N

• Molecular Formula :

  C17H18N8O

• Molecular Weight :

  350.38

• References & Citations :

  [1]Ketan Satish GAJIWALA, et al. Modulators of sting (stimulator of interferon genes) . WO2022195462A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2839639-72-2]