STING modulator-4

• UNSPSC Description:

  STING modulator-4 (compound AIH05) is a competitive STING modulator with a Ki of 0.0933 μM for R232H STING. STING modulator-4 has an EC50 of >10 μM for p-IRF3 in THP-1 cell[1].

• Target Antigen:

  STING

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/sting-modulator-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC2=C(C=NN2C)C(C3=NC(C4=CC=NN4CC)=CN3C)=N1)N

• Molecular Weight:

  350.38

• References & Citations:

  [1]Ketan Satish GAJIWALA, et al. Modulators of sting (stimulator of interferon genes). WO2022195462A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2839639-72-2