Sirtuin modulator 4

• UNSPSC Description:

  Sirtuin modulator 4 (compound 12) is a sirtuin modulator. Sirtuin modulator 4 shows inhibitory effect to SIRT1 with an EC50 value of 51-100 μM. Sirtuin modulator 4 may be used for the research of increasing the lifespan of a cell, and preventing a wide variety of diseases and disorders including, for example, diabetes, obesity, neurodegenerative diseases, cardiovascular diseases, inflammation and cancer[1].

• Target Antigen:

  Sirtuin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/sirtuin-modulator-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC(C(C1=CC2=C(C=CC=C2)O1)=O)C3=NC4=C(S3)C=CC=C4

• Molecular Weight:

  318.35

• References & Citations:

  [1]Milburn Michael, et al. Fused heterocyclic compounds and their use as sirtuin modulators. US7998974. 2011.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  327104-77-8