STING modulator-5

• Description :

  STING modulator-5 (compound 38) is a STING modulator with a pIC50 value of 9.5. STING modulator-5 antagonizes peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1. STING modulator-5 is a antagonist of THP-1 cells, it can be used for immunological disease research[1].

• UNSPSC :

  12352005

• Target :

  STING

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/sting-modulator-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CN(/C1=N\C(C2=CC(C)=NN2CC)=O)C3=CC=CC=C3N1CC(F)(F)C(F)(F)CN4C5=C(OCC6=CC=C(C=C6)OC)C=C(C(N)=O)C=C5N(/C4=N\C(C7=CC(C)=NN7CC)=O)C

• Molecular Formula :

  C43H45F4N11O5

• Molecular Weight :

  871.88

• References & Citations :

  [1]Fosbenner, David T, et al. Modulators of stimulator of interferon genes. WO 2019/069270 Al. 2022.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2305940-22-9]