STING modulator-5

CAT: 0804-HY-148643Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-148643Size:1 Each
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Description
STING modulator-5 (compound 38) is a STING modulator with a pIC50 value of 9.5. STING modulator-5 antagonizes peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1. STING modulator-5 is a antagonist of THP-1 cells, it can be used for immunological disease research[1].
CAS Number
[2305940-22-9]
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sting-modulator-5.html
Solubility
10 mM in DMSO
Smiles
CN(/C1=N\C(C2=CC(C)=NN2CC)=O)C3=CC=CC=C3N1CC(F)(F)C(F)(F)CN4C5=C(OCC6=CC=C(C=C6)OC)C=C(C(N)=O)C=C5N(/C4=N\C(C7=CC(C)=NN7CC)=O)C
Molecular Formula
C43H45F4N11O5
Molecular Weight
871.88
References & Citations
[1]Fosbenner, David T, et al. Modulators of stimulator of interferon genes. WO 2019/069270 Al. 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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