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STING agonist-4

CAT: 0804-HY-123943-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-123943-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STING agonist-4 is an stimulator of Interferon Genes (STING) receptor agonist with an apparent inhibitory constant (IC50) of 20 nM. STING agonist-4 is a two symmetry-related amidobenzimidazole (ABZI) -based compound to create linked ABZIs (diABZIs) with enhanced binding to STING and cellular function[1].
CAS Number
2138300-40-8
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sting-agonist-4.html
Purity
99.97
Solubility
DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=C2N(CCCCN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=CC(C(N)=O)=CC=C35)C(NC(C6=CC(C)=NN6CC)=O)=NC2=C1)N
Molecular Formula
C34H38N12O4
Molecular Weight
678.74
References & Citations
[1]Ramanjulu JM et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Dec;564 (7736) :439-443.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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