STING modulator-4

• Target :

  Others|||STING

• Related Pathways :

  Immunology/Inflammation|||Others

• Bioactivity :

  STING Modulator-4 is a competitive modulator of STING, exhibiting a K_i value of 0.0933 ?M for the R232H STING variant. It demonstrates an EC_50 of over 10 ?M for p-IRF3 activation in THP-1 cells.

• Smiles :

  CN1C(C2=C3C(=CC(C(N)=O)=N2)N(C)N=C3)=NC(=C1)C=4N(CC)N=CC4

• Molecular Formula :

  C17H18N8O

• Molecular Weight :

  350.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2839639-72-2