Antitumor agent-87

CAT: 0804-HY-148592-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-148592-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antitumor agent-87 is a potent antitumor agent. Antitumor agent-87 shows a high affinity for CYP1A1 with a Ki value of 0.23 µM. Antitumor agent-87 shows antiproliferative activity. Antitumor agent-87 induces cell cycle arrest at the G2/M phase. Antitumor agent-87 show antitumoral activity[1].
CAS Number
[1422527-88-5]
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-87.html
Solubility
10 mM in DMSO
Smiles
CCCCCN1CCN(C2=CC=C(S(=O)(OC3=CC(OC)=CC(OC)=C3)=O)C=C2)C1=O
Molecular Formula
C22H28N2O6S
Molecular Weight
448.53
References & Citations
[1]Chavez Alvarez AC, et al. Homologation of the Alkyl Side Chain of Antimitotic Phenyl 4- (2-Oxo-3-alkylimidazolidin-1-yl) benzenesulfonate Prodrugs Selectively Targeting CYP1A1-Expressing Breast Cancers Improves Their Stability in Rodent Liver Microsomes. J Med Chem. 2023 Feb 23;66 (4) :2477-2497.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP1

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