Antitumor agent-53

• Description :

  Antitumor agent-53 is a potent antitumor agent. Antitumor agent-53 induces cell cycle arrest at the G2/M phase. Antitumor agent-53 inhibits the PI3K/AKT pathway to induce the apoptosis of HGC-27 cells. Antitumor agent-53 has the potential for the research of gastrointestinal tumors[1].

• CAS Number :

  [2757145-67-6]

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/antitumor-agent-53.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=C(N(C3C4=C(C5=CC=CC=C5N4)CCN13)C6=CC=CC(F)=C6)C=CC=C2

• Molecular Formula :

  C24H18FN3O

• Molecular Weight :

  383.42

• References & Citations :

  [1]Hao X, et al. Design, synthesis and bioactivity evaluation of novel N-phenyl-substituted evodiamine derivatives as potent anti-tumor agents. Bioorg Med Chem. 2021; 55:116595.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported