STAT3-IN-10

• UNSPSC Description:

  STAT3-IN-10 is a STAT3 inhibitor with an IC50 value of 5.18 μM. STAT3-IN-10 directly binds to STAT3 SH2 domain, induces cancer cells apoptosis[1].

• Target Antigen:

  Apoptosis; STAT

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/stat3-in-10.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC(C=C1)=CC=C1NC2=CC(C3=C(C2=O)OC(C(C)=O)=C3)=O

• Molecular Weight:

  311.29

• References & Citations:

  [1]Kai-Rui Feng, et al. Design, synthesis and biological evaluation of novel potent STAT3 inhibitors based on BBI608 for cancer therapy. Eur J Med Chem. 2020 Sep 1;201:112428.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2499491-04-0