STAT3-IN-10

STAT3-IN-10

• CAS Number: 2499491-04-0
• UNSPSC Description: STAT3-IN-10 is a STAT3 inhibitor with an IC50 value of 5.18 μM. STAT3-IN-10 directly binds to STAT3 SH2 domain, induces cancer cells apoptosis[1].
• Target Antigen: Apoptosis; STAT
• Type: Reference compound
• Related Pathways: Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/stat3-in-10.html
• Solubility: 10 mM in DMSO
• Smiles: COC(C=C1)=CC=C1NC2=CC(C3=C(C2=O)OC(C(C)=O)=C3)=O
• Molecular Weight: 311.29
• References & Citations: [1]Kai-Rui Feng, et al. Design, synthesis and biological evaluation of novel potent STAT3 inhibitors based on BBI608 for cancer therapy. Eur J Med Chem. 2020 Sep 1;201:112428.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported