BChE-IN-7

• Description :

  BChE-IN-7 (compound 13) is a potent, selective, BBB-penetrated and reversible AChE and BChE inhibitor, with an IC50 of 0.06 μM (BChE) . BChE-IN-7 can protect neuronal-like cells from toxic Aβ-species[1].

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/bche-in-7.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OC1CCCN(C1)C2CC3=C(C2)C=CC=C3)NC4=CC=CC=C4

• Molecular Formula :

  C21H24N2O2

• Molecular Weight :

  336.43

• References & Citations :

  [1]Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  BChE

• CAS Number :

  [2416910-85-3]