hCAIX/XII-IN-4

hCAIX/XII-IN-4

• CAS Number: 1119200-33-7
• UNSPSC Description: hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/hcaix-xii-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C=C(C)C2=C(O1)C=C(OCC3=NOC(C4=CC=C(OC)C=C4)=N3)C=C2
• Molecular Weight: 364.35
• References & Citations: [1]Thacker PS, et, al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported