hCAIX/XII-IN-4

• UNSPSC Description:

  hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].

• Target Antigen:

  Carbonic Anhydrase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/hcaix-xii-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C=C(C)C2=C(O1)C=C(OCC3=NOC(C4=CC=C(OC)C=C4)=N3)C=C2

• Molecular Weight:

  364.35

• References & Citations:

  [1]Thacker PS, et, al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1119200-33-7