hCAIX/XII-IN-11

• UNSPSC Description:

  hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII with a Ki value of 0.7 μM for both the isoforms. hCAIX/XII-IN-11 can be used for anticancer research[1].

• Target Antigen:

  Carbonic Anhydrase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hcaix-xii-in-11.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C(N=NN1C2=CC=C(C=C2)F)C(/C=C(C(O)=O)\O)=O

• Molecular Weight:

  291.23

• References & Citations:

  [1]Siwach K, et al. 1,2,3-Triazole-based esters and carboxylic acids as nonclassical carbonic anhydrase inhibitors capable of cathepsin B inhibition. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300372.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported