hCAIX/XII-IN-9

hCAIX/XII-IN-9

• UNSPSC Description: hCAIX/XII-IN-9 (compound 8) is a potent carbonic anhydrase (CA) inhibitor with Ki values of 1658 nM, 184.8 nM, 8.9 nM, 64.8 nM for hCA I, hCA II, hCA IX, and hCA XII, respectively[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/hcaix-xii-in-9.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1N(CCC2=CC=C(S(=O)(N)=O)C=C2)C(SCC(N/N=C/C3=C(OC)C=CC=C3)=O)=NC4=CC=CC=C41
• Molecular Weight: 551.64
• References & Citations: [1]Adel S El-Azab, et al. Design, synthesis, and carbonic anhydrase inhibition activities of Schiff bases incorporating benzenesulfonamide scaffold: Molecular docking application. Saudi Pharm J. 2023 Dec;31(12):101866.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported