hCAIX/XII-IN-7

hCAIX/XII-IN-7

• UNSPSC Description: hCAIX/XII-IN-7 (compound 3e) is a potent hCA IX and XII inhibitor with Kis of 3.2 nM, 9.2 nM, 503.7 nM and 59 nM for hCA I, hCA II, hCA IX and hCA XII, respectively. hCAIX/XII-IN-7 has the potential for hypoxic tumors research[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hcaix-xii-in-7.html
• Solubility: 10 mM in DMSO
• Smiles: N#CC1=CC=C(N(N=C/2C)C(C2=N\NC(C=C3)=CC=C3S(=O)(N)=O)=O)C=C1
• Molecular Weight: 382.40
• References & Citations: [1]Suleyman Akocak, et al. Potent and selective carbonic anhydrase inhibition activities of pyrazolones bearing benzenesulfonamides. Bioorg Med Chem Lett. 2023 Oct 15:95:129479.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported