Antitumor agent-62

• Description :

  Antitumor agent-62 (Compound 47) is a NO-releasing antitumor agent. Antitumor agent-62 shows antiproliferative activity against four cancer cell lines. Antitumor agent-62 activates mitochondrial apoptosis pathway and arrests cell cycle at G2/M phase[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/antitumor-agent-62.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1OC2=C(C=C1N)C=C(OC)C(OCCCOC3=NO[N+]([O-])=C3S(=O)(C4=CC=CC=C4)=O)=C2

• Molecular Formula :

  C21H19N3O9S

• Molecular Weight :

  489.46

• References & Citations :

  [1]Shi Z, et al. Novel NO-releasing scopoletin derivatives induce cell death via mitochondrial apoptosis pathway and cell cycle arrest. Eur J Med Chem. 2020 Aug 15;200:112386.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2460735-29-7]