Products for Research Use Only
RegisterLogin

PCSK9 modulator-3

CAT: 0804-HY-146084Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-146084Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PCSK9 modulator-3 (Compound 13) is a potent modulator of PCSK9 with an EC50 value of 2.46 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C) . PCSK9 modulator-3 has the potential for the research of hyperlipidemia[1].
CAS Number
2476490-18-1
UNSPSC
12352005
Target
PCSK9
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pcsk9-modulator-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC2=CC=C(F)C=C2N1)C3=CNC4=C3C=CC=C4F
Molecular Formula
C16H9F2N3O
Molecular Weight
297.26
References & Citations
[1]Xie H, et al. From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators. Eur J Med Chem. 2020 Nov 15;206:112678.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-128334PCSK9 modulator-2
HY-146085PCSK9 modulator-4
HY-139998PCSK9-IN-3
HY-161903-01Progranulin modulator-3
HY-148606STING modulator-3
HY-128830Kv3 modulator 3
HY-176062PPARγ modulator-3
HY-160083KCC2 Modulator-3
HY-175672MRGPRX4 modulator-3
HY-147529MGluR2 modulator 3

Alternative Products

CatalogName
T60646-01PCSK9 modulator-3
GTR19187700-01PCSK9 modulator-4
T60541-01PCSK9 modulator-2
T74167-01PCSK9-IN-3
BZ64546PCMV6-PCSK9-3*FLAG
PVT10294pECMV-3*Flag-PCSK9 Plasmid
SC213563PCSK9 (NM_174936) Human 3' UTR Clone
TU017595PCSK9 3'UTR Luciferase Stable Cell Line
K7443104Pcsk9 sgRNA CRISPR Lentivector (Rat) (Target 3)
36238081PCSK9 3'UTR Lenti-reporter-Luc Vector

Popular Products