Antitumor agent-56

• UNSPSC Description:

  Antitumor agent-56 (Compound 33) is a triptolide derivative with antitumor, anti-inflammatory and NO release activities. Antitumor agent-56 significantly inhibits the growth of melanoma. Antitumor agent-56 is orally active[1].

• Target Antigen:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/antitumor-agent-56.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]12[C@@]34[C@@]5([C@@](C[C@@]1([H])C6=C(C(OC6)=O)CC2)([H])O5)[C@@H]([C@@]7([C@](O7)([H])[C@]3([H])O4)C(C)C)OC8=NO[N+]([O-])=C8S(=O)(C9=CC=CC=C9)=O

• Molecular Weight:

  584.59

• References & Citations:

  [1]Zang Y, et al. Novel nitric oxide-releasing derivatives of triptolide as antitumor and anti-inflammatory agents: Design, synthesis, biological evaluation, and nitric oxide release studies. Eur J Med Chem. 2020 Mar 15;190:112079.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4