Antitumor agent-56

• Description:

  Antitumor agent-56 (Compound 33) is a triptolide derivative with antitumor, anti-inflammatory and NO release activities. Antitumor agent-56 significantly inhibits the growth of melanoma. Antitumor agent-56 is orally active[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/antitumor-agent-56.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]12[C@@]34[C@@]5 ([C@@] (C[C@@]1 ([H]) C6=C (C (OC6) =O) CC2) ([H]) O5) [C@@H] ([C@@]7 ([C@] (O7) ([H]) [C@]3 ([H]) O4) C (C) C) OC8=NO[N+] ([O-]) =C8S (=O) (C9=CC=CC=C9) =O

• Molecular Formula:

  C28H28N2O10S

• Molecular Weight:

  584.59

• References & Citations:

  [1]Zang Y, et al. Novel nitric oxide-releasing derivatives of triptolide as antitumor and anti-inflammatory agents: Design, synthesis, biological evaluation, and nitric oxide release studies. Eur J Med Chem. 2020 Mar 15;190:112079.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2411579-53-6