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Antitumor agent-55

CAT: 0804-HY-146038Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146038Size:1 Each
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Description
Antitumor agent-55 (compound 5q) is a potent antitumor agent. Antitumor agent-55 effectively inhibits PC3, with an IC50 of 0.91 μM. Antitumor agent-55 effectively inhibits the colony formation, suppresses the cell migration in PC3. Antitumor agent-55 induces G1/S phase arrest and apoptosis in PC3[1].
CAS Number
2522594-49-4
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; MDM-2/p53; ROS Kinase
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-55.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1CN(C2=CC(C)=NC3=NC(SCC4=C5C=CC=CC5=CC=C4)=NN23)CCC1)C6=CC(OC)=C(OC)C(OC)=C6
Molecular Formula
C32H34N6O4S
Molecular Weight
598.72
References & Citations
[1]Lu N, Huo JL, Wang S, Yuan XH, Liu HM. Drug repurposing: Discovery of troxipide analogs as potent antitumor agents. Eur J Med Chem. 2020;202:112471.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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