Antitumor agent-45

CAT: 0804-HY-144394Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-144394Size:1 Each
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Description
Antitumor agent-45 (Compound 21) could induce and stimulate A549 cells apoptosis in G0/G1 and G2/M phase. Antitumor agent-45 (Compound 21) inhibits c-Met expression to regulate the growth of tumor cells[1].
CAS Number
[2581082-74-6]
UNSPSC
12352005
Target
Apoptosis; c-Met/HGFR
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-45.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN(C2=NC=CC=C2C1=O)C3=CC=C(C=C3)Br)NC4=CC=C(C(F)=C4)OC5=CC=NC6=C5C=CN6
Molecular Formula
C28H17BrFN5O3
Molecular Weight
570.37
References & Citations
[1]Jianqing Zhang, et al. Synthesis, bioevaluation and molecular dynamics of pyrrolo-pyridine benzamide derivatives as potential antitumor agents in vitro and in vivo. Eur J Med Chem. 2022 Apr 5;233:114215.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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