Antitumor agent-43

• Description :

  Antitumor agent-43 (Compound 4B) is a potent antitumor agent, with an IC50of 0.5 μM for (T-24 cell) . Antitumor agent-43 (Compound 4B) induces cell cycle arrest at G2/M phase[1].

• CAS Number :

  [2766035-37-2]

• UNSPSC :

  12352005

• Target :

  Apoptosis; DNA/RNA Synthesis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/antitumor-agent-43.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=NC=CC3=C([N+]([O-])=O)C=CC(C4=C1C=CC=C4)=C23

• Molecular Formula :

  C16H8N2O3

• Molecular Weight :

  276.25

• References & Citations :

  [1]Lan-Shan Liao, et al. One-pot synthesis of oxoaporphines as potent antitumor agents and investigation of their mechanisms of actions. Eur J Med Chem

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported