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Antitumor agent-42

CAT: 0804-HY-144331Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144331Size:1 Each
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Description
Antitumor agent-42 (Compound 15h) is a bifunctional agent exhibiting both tubulin polymerized inhibition and NO-releasing activities, resulting in potent anti-angiogenesis, colony formation inhibition, cell cycle arrest and apoptosis induction effects[1].
CAS Number
2763621-91-4
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-42.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1OCCOC2=NO[N+]([O-])=C2S(=O)(C3=CC=CC=C3)=O)C(C4=CC=C(C=C4)Br)=O
Molecular Formula
C24H19BrN2O8S
Molecular Weight
575.39
References & Citations
[1]Xin Huang, et al. Synthesis and biological evaluation of novel hybrids of phenylsulfonyl furoxan and phenstatin derivatives as potent anti-tumor agents. Eur J Med Chem. 2022 Feb 15; 230:114112.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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