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STING agonist-13

CAT: 0804-HY-143321Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143321Size:1 Each
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Description
STING agonist-13 is a stimulator of interferon genes (STING) agonist, for cancer immunity via STING-mediated immune activation. STING agonist-13 can stimulate STING downstream signaling and promoting type I interferon immune responses. STING agonist-13 significantly decreases tumor volume and shows immunological memory-derived cancer inhibition[1].
CAS Number
2816929-48-1
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sting-agonist-13.html
Solubility
10 mM in DMSO
Smiles
CCN1N=C(C=C1C(NC2=NC3=C(N2C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=CC(C(N)=O)=CC(OCCCNC(C7=CC(C)=NN7CC)=O)=C64)C(OC)=CC(C(N)=O)=C3)=O)C
Molecular Formula
C45H53N15O7
Molecular Weight
916.00
References & Citations
[1]Jeon MJ, L, et al. Development of Potent Immune Modulators Targeting Stimulator of Interferon Genes Receptor. J Med Chem. 2022 Apr 14;65 (7) :5407-5432.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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