Products for Research Use Only
RegisterLogin

STING agonist-14

CAT: 0804-HY-139179-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-139179-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
STING agonist-14 (compound 12b) is a potent STING agonist that is efficacious across species. STING agonist-14 could activate the pathway by directly binding human STING. STING agonist-14 can be used for the research of tumours or viral infections[1].
CAS Number
2411100-70-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/sting-agonist-14.html
Purity
99.9
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C(C)=C(C)C=C2)NC3=CC=C(OC)C=C13
Molecular Formula
C16H15NO2
Molecular Weight
253.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Hou S, et, al. Design, synthesis and biological evaluation of acridone analogues as novel STING receptor agonists. Bioorg Chem. 2020 Jan:95:103556.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

Chemical Information

STING Agonist 12b
CAS Number2411100-70-2
PubChem CID156118667
IUPAC Name2-methoxy-5,6-dimethyl-10H-acridin-9-one
Molecular FormulaC16H15NO2
Molecular Weight253.29
XLogP3.7
Topological Polar Surface Area38.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count19
Formal Charge0
Complexity357
SMILES
CC1=C(C2=C(C=C1)C(=O)C3=C(N2)C=CC(=C3)OC)C
InChI
InChI=1S/C16H15NO2/c1-9-4-6-12-15(10(9)2)17-14-7-5-11(19-3)8-13(14)16(12)18/h4-8H,1-3H3,(H,17,18)
InChIKey
SEVGTQHWWAYAQR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of STING Agonist 12b
CAS: 2411100-70-2
CID: 156118667
Formula: C16H15NO2
MW: 253.29
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight253.29
XLogP33.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass253.110278721
Monoisotopic Mass253.110278721
Topological Polar Surface Area38.3 Ų
Heavy Atom Count19
Formal Charge0
Complexity357
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-149267-01STING agonist-30
HY-152958STING agonist-25
HY-152960STING agonist-27
HY-144328STING agonist-10
HY-143896-01STING agonist-7
HY-178966STING agonist-48
HY-177338STING agonist-45
HY-176257STING agonist-44
HY-147834STING agonist-9
HY-152956-01STING agonist-23

Alternative Products

CatalogName
463304STING Agonist 12b
T207376-01STING agonist-42
T72688-01STING agonist-20
T63457-01STING agonist-10
T83841-01STING Agonist D61
T13014-01STING agonist-3
T75093-01STING agonist-25
T74268-01STING agonist-13
B2047-5STING AGONIST G10
MBS3611610-01STING agonist-1

Popular Products