STING agonist-10

CAT: 0804-HY-144328Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-144328Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
STING agonist-10 (Compound 91) is a potent small molecule cyclic urea activator of STING with the EC50 of 2600 nM. Activation of STING is a highly promising approach in immunotherapy[1].
CAS Number
[2259308-69-3]
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/sting-agonist-10.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=C(C=C1)[C@@H](C)N(C)C(N2CC3=C(F)C=CC=C3Cl)=O)NCC4=C(F)C=C(F)C=C4F
Molecular Formula
C25H20ClF4N3O2
Molecular Weight
505.89
References & Citations
[1]Sourav Basu, et al. The discovery of potent small molecule cyclic urea activators of STING. Eur J Med Chem. 2022 Feb 5;229:114087.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-152956-01STING agonist-23
HY-152960STING agonist-27
HY-178966STING agonist-48
HY-177338STING agonist-45
HY-176257STING agonist-44
HY-152958STING agonist-25
HY-147834STING agonist-9
HY-150074STING agonist-18
HY-139179-01STING agonist-14
HY-143896-01STING agonist-7

Alternative Products

CatalogName
MF-0139417-01STING agonist-10
MBS3611610-01STING agonist-1
MBS3844334-01STING agonist-3
7741/10STING agonist C53
MBS3615094-01STING agonist-4
MBS5814996STING agonist-20
MBS5817016STING agonist-25
MBS5817017STING agonist-26
MBS5806128STING agonist-11
MBS5816247STING agonist-17

Popular Products