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STING agonist-25

CAT: 0931-T75093-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T75093-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2408723-10-2
Target
Others, STING
Related Pathways
Immunology/Inflammation, Others
Bioactivity
STING agonist-23 (CF505) is a non-nucleotide, small-molecule compound that stimulates STING, enhancing the phosphorylation of STING, TBK1, and IRF3. It elevates the production of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells and demonstrates efficacy against SARS-CoV strains [1].
Smiles
C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCCO
Molecular Formula
C36H41N13O6
Molecular Weight
751.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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