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EGFR-IN-23

CAT: 0804-HY-142680Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142680Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-23 is a potent EGFR TKI (tyrosine kinase inhibitor) with an IC50 of 8.05 nM for BaF3/EGFR-DEL19/T790M/C797S cell (WO2021244502A1, compound 8) [1].
CAS Number
2747133-37-3
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-23.html
Solubility
10 mM in DMSO
Smiles
CN1N=CC(C2=C(N3CCC(CN4CCOCCC4)CC3)C=C(OC)C(NC5=NC=C(Br)C(NC6=CC=C7N=CC=NC7=C6P(C)(C)=O)=N5)=C2)=C1
Molecular Formula
C36H44BrN10O3P
Molecular Weight
775.68
References & Citations
[1]Polyaryl compound and use. WO2021244502A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported