SKF 83509

CAT: 0804-HY-111160Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-111160Size:1 Each
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Description
SKF 83509, a desmethyl analogue of SCH 23390 (HY-19545A), is a selective dopamine D1 antagonist with a Ki of 70.2 nM. SKF 83509 has no activity at dopamine D2 receptors[1].
CAS Number
[90955-43-4]
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/skf-83509.html
Smiles
OC1=C(Cl)C=C2CCNCC(C3=CC=CC=C3)C2=C1.Br
Molecular Formula
C16H17BrClNO
Molecular Weight
354.67
References & Citations
[1]Y Itoh, M Beaulieu, et al. The chemical basis for the blockade of the D-1 dopamine receptor by SCH 23390. Eur J Pharmacol. 1984 Apr 13;100 (1) :119-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D2 Receptor

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