EGFR-IN-23

CAT: 0931-T73104-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T73104-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2747133-37-3

Target

EGFR, Others

Related Pathways

JAK/STAT signaling, Others, Angiogenesis, Tyrosine Kinase/Adaptors

Bioactivity

EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.05 nM against the BaF3/EGFR-DEL19/T790M/C797S cell line.

Smiles

N(C1=CC(=C(C=C1OC)N2CCC(CN3CCCOCC3)CC2)C=4C=NN(C)C4)C=5N=C(NC6=C(P(C)(C)=O)C7=C(C=C6)N=CC=N7)C(Br)=CN5

Molecular Formula

C36H44BrN10O3P

Molecular Weight

775.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
HY-142680	EGFR-IN-23
sc-80543	EGFR (EGFR.1)
I8443-42D	Interleukin 23 (IL-23)
MBS343261-01	Interleukin-23 (IL-23)
E21-S31	Interleukin-23/IL-23
ant-042	EGFR

EGFR-IN-23

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