Products for Research Use Only
RegisterLogin

CDK2-IN-23

CAT: 0804-HY-162255-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-162255-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CDK2-IN-23 (Compound 17) is a kinase selective and highly potent CDK2 inhibitor (IC50 = 0.29 nM) . CDK2-IN-23 shows the pharmacodynamic inhibition of CDK2 in CCNE1-amplified mouse models. CDK2-IN-23 can be used for the research of cancer[1].
CAS Number
2488073-20-5
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk2-in-23.html
Purity
99.22
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(O)(CN1C=C(C2=C(C(F)(F)F)C=NC(NC3CCN(S(=O)(C4CC4)=O)CC3)=N2)C=N1)C
Molecular Formula
C20H27F3N6O3S
Molecular Weight
488.53
References & Citations
[1]Hummel JR, et al. Discovery of (4-Pyrazolyl) -2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2. J Med Chem. 2024 Feb 22;67 (4) :3112-3126.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-153426CDK9-IN-23
HY-P0235CDK2
HY-168444CDK4/6-IN-23
HY-134622-01GSK-3/CDK5/CDK2-IN-1
HY-173310CDK2-IN-44
HY-173203CDK2-IN-43
HY-172153CDK2-IN-41
HY-170441CDK2-IN-36
HY-169683CDK2-IN-39
HY-160185CDK2-IN-21

Alternative Products

CatalogName
T86028-01CDK2-IN-23
C07088-100mgCDK2-IN-73 (CDK2-IN-4)
310216-01CDK2

Popular Products