Antitumor agent-28

• UNSPSC Description:

  Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity[1].

• Target Antigen:

  ATM/ATR

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/antitumor-agent-28.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1C(C)C)N(C)C2=C1C3=CC(C4=CC=C(N5CC(N(C)C)C5)N=C4)=CC=C3N=C2.CS(=O)(O)=O

• Molecular Weight:

  512.62

• References & Citations:

  [1]Kurt Gordon Pike, et al. Composés imidazo[4,5c]quinoline-2-one et leur utilisation dans le traitement du cancer. WO2017076898A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4