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Antitumor agent-28

CAT: 0804-HY-141478Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-141478Size:1 Each
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Description
Antitumor agent-28 selectively inhibits ataxia telangiectasia mutated (ATM) kinase. Antitumor agent-28 prevents ATM mediated disease and has potent anti-cancer activity[1].
CAS Number
2097499-67-5
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-28.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C(C)C)N(C)C2=C1C3=CC(C4=CC=C(N5CC(N(C)C)C5)N=C4)=CC=C3N=C2.CS(=O)(O)=O
Molecular Formula
C25H32N6O4S
Molecular Weight
512.62
References & Citations
[1]Kurt Gordon Pike, et al. Composés imidazo[4,5c]quinoline-2-one et leur utilisation dans le traitement du cancer. WO2017076898A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ATM; ATR

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