PROTAC IRAK4 degrader-6

PROTAC IRAK4 degrader-6

• CAS Number: 2360530-72-7
• UNSPSC Description: PROTAC IRAK4 degrader-6 is a Cereblon-based PROTAC as interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-172[1].
• Target Antigen: IRAK; PROTACs
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;PROTAC
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-irak4-degrader-6.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=NN(C2=CC=C(C(NCCCCCNCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)=O)C=C2)C=C1NC(C6=COC(C7=CC(NCC(F)(F)F)=NC=C7)=N6)=O)N
• Molecular Weight: 898.85
• References & Citations: [1]https://scifinder-n.cas.org/patent-viewer?docuri=g__2-GF3YbbKfwweYAYLNnmYDIpK1sFeQGP9cmlPB_4&markedFullTextKey=GFB6kc_cFl60fBy8t-u8qupJE998gaydSFApjgE-p5c.pdf
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported