PROTAC IRAK4 degrader-6

• UNSPSC Description:

  PROTAC IRAK4 degrader-6 is a Cereblon-based PROTAC as interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-172[1].

• Target Antigen:

  IRAK; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation;PROTAC

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-irak4-degrader-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NN(C2=CC=C(C(NCCCCCNCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)=O)C=C2)C=C1NC(C6=COC(C7=CC(NCC(F)(F)F)=NC=C7)=N6)=O)N

• Molecular Weight:

  898.85

• References & Citations:

  [1]https://scifinder-n.cas.org/patent-viewer?docuri=g__2-GF3YbbKfwweYAYLNnmYDIpK1sFeQGP9cmlPB_4&markedFullTextKey=GFB6kc_cFl60fBy8t-u8qupJE998gaydSFApjgE-p5c.pdf

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2360530-72-7