PROTAC IRAK4 degrader-3

• CAS Number:

  2374122-43-5

• UNSPSC Description:

  PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau[1].

• Target Antigen:

  IRAK; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation;PROTAC

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/protac-irak4-degrader-3.html

• Smiles:

  CC[C@H]([C@@H](C(N1)=O)F)[C@H]1COC2=NC=C(C#CCN3CCC4(CCN(C5=NC=C(C(N[C@H](C(C)(C)C)C(N6[C@H](C[C@@H](C6)O)C(NCC7=CC=C(C8=C(N=CS8)C)C=C7)=O)=O)=O)C=N5)CC4)CC3)C9=C2C=C(OC)C(C(N)=O)=C9

• Molecular Weight:

  1086.28

• References & Citations:

  [1]Nunes J, et al. Targeting IRAK4 for Degradation with PROTACs. ACS Med Chem Lett. 2019;10(7):1081-1085. Published 2019 Jun 14.

• Shipping Conditions:

  Blue Ice