PROTAC IRAK4 degrader-5

• UNSPSC Description:

  PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader extracted from patent US20190192668A1, compound I-171[1].

• Target Antigen:

  IRAK; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation;PROTAC

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-irak4-degrader-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NN(C2=CC=C(CNCCOCCOCCNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)C=C2)C=C1NC(C6=COC(C7=CC(NCC(F)(F)F)=NC=C7)=N6)=O)N

• Molecular Weight:

  887.82

• References & Citations:

  [1]Mainolfi N, et, al. Irak degraders and uses thereof. US20190192668A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2360530-61-4