SK-216

• Description:

  SK-216 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor that acts as an anti-metastatic agent for human osteosarcoma and inhibits lung metastasis of human osteosarcoma[1].

• UNSPSC:

  12352005

• Target:

  PAI-1

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sk-216.html

• Purity:

  99.43

• Solubility:

  H2O : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(O[Na])C(CCCCCOC1=CC=C2C=C(C3=NC4=CC(C(C)(C)C)=CC=C4O3)C=CC2=C1)C(O[Na])=O

• Molecular Formula:

  C29H29NNa2O6

• Molecular Weight:

  533.52

• References & Citations:

  [1]Minori Tsuge, et al. SK-216, a Novel Inhibitor of Plasminogen Activator Inhibitor-1, Suppresses Lung Metastasis of Human Osteosarcoma. Int J Mol Sci. 2018 Mar 5;19 (3) :736.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [654080-03-2]