SK-7041

• Description:

  SK-7041 is a HDAC inhibitor with the IC50 of 172 nM. SK-7041 induces the hyperacetylation of histones H3 and H4 .SK-7041 inhibits tumor cell growth in vivo and in vitro, induces cell apoptosis, and arrests cell cycle at the G1 phase[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; HDAC

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Cell Cycle/DNA Damage; Epigenetics

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sk-7041.html

• Smiles:

  ONC(/C=C/C(C=C1)=CC=C1CNC(C2=CC=C(C=C2)N(C)C)=O)=O

• Molecular Formula:

  C19H21N3O3

• Molecular Weight:

  339.39

• References & Citations:

  [1]Park JH, et al. Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation. Clin Cancer Res. 2004;10 (15) :5271-5281.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  617690-98-9