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LW-216

CAT: 0804-HY-163724Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163724Size:1 Each
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Description
LW-216 is a TrxR1 inhibitor that induces Apoptosis. LW-216 has anti-tumor activity[1].
CAS Number
2146090-18-6
UNSPSC
12352005
Target
Apoptosis; TrxR
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lw-216.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=CC=CC=C2)OC3=C(C(OCC4=CC=CC=C4)=CC(O)=C13)OCCCCN5CCCC5
Molecular Formula
C30H31NO5
Molecular Weight
485.57
References & Citations
[1]Wang R, et al. Inducing ubiquitination and degradation of TrxR1 protein by LW-216 promotes apoptosis in non-small cell lung cancer via triggering ROS production. Neoplasia. 2024 Jul;53:101004
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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