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SDZ 216-525

CAT: 0804-HY-116309Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116309Size:1 Each
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Description
SDZ 216-525 is a selective silent antagonist of 5-HT1A receptor[1][2].
CAS Number
141533-35-9
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sdz-216-525.html
Smiles
O=C(C(N1)=CC2=C1C=CC=C2N3CCN(CCCCN(C(C4=C5C=CC=C4)=O)S5(=O)=O)CC3)OC
Molecular Formula
C25H28N4O5S
Molecular Weight
496.58
References & Citations
[1]Boddeke H W G M, et al. Agonist/antagonist interactions with cloned human 5-HT 1A receptors: variations in intrinsic activity studied in transfected HeLa cells[J]. Naunyn-Schmiedeberg's archives of pharmacology, 1992, 345: 257-263.|[2]Sharp T, et al. The novel 5‐HT1A receptor antagonist, SDZ 216–525, decreases 5‐HT release in rat hippocampus in vivo[J]. British journal of pharmacology, 1993, 109 (3) : 699-702.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor

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